The usual dose of amantadine hydrochloride is 100 mg twice a day. Occasionally, patients whose responses are not optimal with amantadine hydrochloride at 200 mg daily may benefit from an increase up to 300 mg daily in divided doses.
Depending upon creatinine clearance, the following dosage adjustments are recommended:
|CREATININE CLEARANCE (mL/min/1.73m2)
||AMANTADINE HYDROCHLORIDE DOSAGE|
|30 to 50||200 mg 1st day and 100 mg each day thereafter
|15 to 29||200 mg 1st day followed by 100 mg on alternate days
|<15||200 mg every 7 days|
The recommended dosage for patients on hemodialysis is 200 mg every 7 days.
NDC:17856-0093-3 in a CUP, UNIT-DOSE of 5 SOLUTIONS
Store at 20° to 25°C (68° to 77°F), excursions permitted to 15° to 30°C (59° to 86°F). [See USP Controlled Room Temperature].
KEEP TIGHTLY CLOSED
Dispense in a tight container as defined in the USP, with a child-resistant closure (as required).
W.W. Wilson and A.H. Rajput, Amantadine-Dyazide Interaction, Can. Med. Assoc. J. 129:974–975, 1983. 1
D.F. Casey, N. Engl. J. Med. 298:516, 1978. 2
C.D. Berkowitz, J. Pediatr. 95:144, 1979. 3
Product No.: 8093
Manufactured for: Wockhardt USA, LLC Parsippany, NJ 07054
Manufactured By: Morton Grove Pharmaceuticals, Inc. Morton Grove, IL 60053
ATLANTIC BIOLOGICALS CORP.
MIAMI, FL 33179
| AMANTADINE HYDROCHLORIDE |
amantadine hydrochloride solution
|Labeler — Atlantic Biologicals Corps (047437707)|
|Registrant — Atlantic Biologicals Corps (047437707)|
|Atlantic Biologicals Corps||047437707||RELABEL (17856-0093), REPACK (17856-0093)|
Revised: 05/2020 Atlantic Biologicals Corps
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